AZILECT PACKAGE INSERT PDF

Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Azilect (rasagiline). 21/06/ Azilect – EMEA/H/C/ – IA//G. List item. Azilect: EPAR – Product Information (PDF/ KB) of the marketing authorisation; Annex IIIA – Labelling; Annex IIIB – Package leaflet. PACKAGE LEAFLET: INFORMATION FOR THE USER. AZILECT 1 mg tablets. Rasagiline. Read all of this leaflet carefully before you start.

Author: Shakalkis Vudole
Country: Chile
Language: English (Spanish)
Genre: Environment
Published (Last): 17 October 2018
Pages: 417
PDF File Size: 5.32 Mb
ePub File Size: 16.92 Mb
ISBN: 237-4-50764-878-4
Downloads: 41207
Price: Free* [*Free Regsitration Required]
Uploader: Arashilabar

Flu-like symptoms, feeling unwell, aches and pains, loss of appetite, feeling depressed, increased urgency to pass urine, conjunctivitis, unusual dreams and thoughts.

Contact their healthcare provider if elevation of blood pressure occurs. Effect of rasagiline on Other Drugs: Very common rasagiline side-effects – these affect more than 1 in 10 people who take this medicine. Signs and symptoms may not appear immediately – may have delays of up to 12 hours after ingestion of drug and the appearance of signs.

This article is for information only and should not be used for the diagnosis or treatment of medical conditions. You are therefore advised to be selective about which sections or aazilect you wish to print.

Did you find this information useful? Health Tools Feeling unwell? No additional in vivo trials have investigated the effect of rasagiline on other drugs metabolized by the cytochrome P enzyme system. The elevated dopamine level and subsequent increased dopaminergic activity are likely to mediate rasagiline’s beneficial effects seen in models of dopaminergic motor dysfunction.

Inform patients that hallucinations or other manifestations of psychotic-like behavior can occur when taking rasagiline. Very common rasagiline side-effects – these affect more than 1 in 10 people who take this medicine What can I do if I experience this?

The mean volume of distribution at steady-state is 87 L, indicating that the tissue binding of rasagiline is in excess of plasma protein binding. Thank you, we just sent a survey email to confirm your preferences.

  CRB455E DATASHEET PDF

Neurotransmitters are chemicals that allow nerve cells to communicate with one another. John’s Wort, cyclobenzaprine or another selective or non-selective MAO inhibitor. Mild impairment, Child-Pugh Class Veterinary regulatory Overview Research and development Marketing authorisation Post-authorisation. No significant differences in the safety profile of geriatric and non-geriatric patients. Advise patients about the potential for sedating effects associated with rasagiline, including somnolence and particularly to the possibility of falling asleep while engaged in activities of daily living.

Specific Populations Hepatic Impairment: If you need more information about your medical condition or your treatment, read the package leaflet also part of the EPAR or contact your doctor or pharmacist. Support respiration; monitor body temperature; intensive management of hyperpyrexia may be required; maintenance of fluid and electrolyte balance is essential.

Rasagiline Tablets

Instruct patients to take the medicine as prescribed. MAO regulates the metabolic degradation of catecholamines and serotonin in the CNS and peripheral tissues. Advise healthcare provider if any new urges develop or increase in frequency. Treatments for psychosis may decrease the effectiveness of rasagiline. The marketing authorisation was renewed on 21 February Swensweg 5 GA Haarlem Netherlands.

Rasagiline for Parkinson’s disease (Azilect) | Patient

Thanks for your feedback. Anatomical therapeutic chemical ATC code. Advise patients that they may experience intense urges to gamble, increased sexual urges, other intense urges, and the inability to control these urges during treatment. We’d love to send you our articles and latest news by email, giving you the best opportunity to stay up to date with expert written health and lifestyle content.

The product catalog provides you with a full listing of Teva’s brand and generic product lines. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once.

May cause hypertension including severe hypertensive syndromes at recommended doses May cause serotonin syndrome when used with antidepressants May cause falling asleep during activities of daily living, daytime drowsiness, and somnolence May cause hypotension, especially orthostatic May cause or exacerbate dyskinesia.

  AS BRUMAS DE AVALON VOLUME 4 PDF

The results of a clinical trial designed to examine the effects of the drug on blood pressure when it is administered with increasing doses of tyramine indicates the functional selectivity can be incomplete when healthy subjects ingest large amounts of tyramine while receiving recommended doses of rasagiline.

If you experience any other symptoms which you aizlect may be due to this medicine, speak with your doctor or pharmacist. Common rasagiline side-effects – these affect less than 1 in 10 people who take this medicine. Dosage adjustment for mild impairment; do not use in moderate or severe impairment. In vitro metabolism studies showed that CYP1A2 was the major enzyme responsible for the metabolism of rasagiline. Headache Ask your pharmacist or doctor to recommend a suitable painkiller Uncontrolled movements Let your doctor know about this Common rasagiline side-effects – these affect less than 1 in 10 people who take this medicine What can I do if I experience this?

Teva’s generic of AZILECT® Tablets: Rasagiline Tablets

If a doss is missed, the patient should not double the dose. In vitro experiments indicate that both routes of rasagiline aziect are dependent on the cytochrome P CYP system, with CYP1A2 being the major isoenzyme involved in rasagiline metabolism.

Studies in healthy subjects and in Parkinson’s disease patients have shown that rasagiline inhibits platelet MAO-B irreversibly.

It is not recommended for patients with moderate liver problems. In ex vivo animal studies in brain, liver, and intestinal tissues, rasagiline azilevt shown to be a potent, irreversible monoamine oxidase type B MAO-B selective inhibitor.

Azilect must not be used in patients who have severe problems with their liver. Are generic drugs as safe as brand-name drugs? Please enter text to search.